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Artificial intelligence can support target identification, clinical trial design, biomarker discovery, patient stratification, real-world evidence generation, and safety monitoring

A Cochrane systematic review of 11 trials examined magnesium supplementation for muscle cramps, finding a generally favorable safety profile across different populations (PMID: 32956536)

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doi:10.1016/0022-4731(87)90200-7

Of note, many of these cases exhibit CSF oligoclonal bands, Gd-enhancing lesions on MRI and clinical response to immunosuppressionall features very typical of MSindicating that secondary immune responses to a primary trigger can play a significant role in the final clinical phenotype