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From a genetic point of view, ferroptosis is a complex biological process correlated to metabolic disturbances in several biological processes, including iron homeostasis, fatty acid synthesis, and lipid oxidation, which are regulated by an organized network of genes (28)

3.67 times higher risk of gastroparesis , or stomach paralysis, which limits the passage of food from the stomach to the small intestine and results in symptoms like vomiting, nausea and abdominal pain

doi: 10.1016/S0140-6736(23)01200-X

Moreover, a 7.5% (58 mmol/mol) intensification threshold was tested in a sensitivity analysis, leading to more positive results for oral semaglutide and demonstrating the 8.0% (64 mmol/mol) threshold as a conservative assumption (Fig

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