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Although HDACi face challenges in clinical application, such as poor water solubility, rapid clearance, and high systemic toxicity, their effectiveness in inhibiting tumor growth and metastasis has been supported by numerous studies (111)

Statins are prescribed worldwide due to their capacity of lowering the cholesterol levels

leading to alpha helix formation

In the Phase 2b trial (2007, n=536) AOD-9604 showed weight reduction only 0.3 kg greater than placebo after 24 weeks

Protection: The liposomal technology ensures that the fragile tripeptide is protected from the harsh environment of the gut

Cuts may also bleed longer