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Last updated April 2026 Sources verified against the Zepbound FDA prescribing information, NEJM SURMOUNT-1 (Jastreboff et al., 2022), and Lillys Zepbound consumer page

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17 Clinical outcome of adjuvant tamoxifen in postmenopausal patients is influenced by their CYP2D6 metabolizer phenotype which can be predicted by genetic testing 18, 19, 20 using germline rather than tumor DNA