But doctors say it takes more than a regular shot for patients to achieve their weight goals in the long run
While the GLP-1RA drugs have traditionally been used in type 2 diabetics, their ability to cause weight loss has captured the minds and imaginations of patients, providers, and drug manufacturers alike
Vilsboll T, Christensen M, Junker AE, Knop FK, Gluud LL
One study found that over 90% of GLP1 users failed to meet requirements for Vitamin D, potassium and choline (Spreckley 2026)
And this all starts with a conversation with a licensed provider who can take the full picture into account and who understands your specific health needs
Patients should contact their GP or healthcare provider promptly if they experience: Sudden or rapid swelling of the ankles, feet, or legs Facial swelling , particularly involving the lips, tongue, or throat (which may indicate angioedemaa medical emergency) [4] Swelling accompanied by shortness of breath , chest pain, or difficulty breathing Significant weight gain (more than 23 kg in a few days) without clear dietary explanation Swelling associated with abdominal distension or discomfort Reduced urine output or changes in urine colour Hot, red, painful swelling in one leg (which could indicate deep vein thrombosis) Seek immediate medical attention (call 999 or attend A&E) if swelling is accompanied by: Severe difficulty breathing or wheezing Chest pain or pressure Swelling of the face, lips, or tongue that affects breathing or swallowing Sudden severe abdominal pain (which could indicate pancreatitis, a rare but serious GLP-1 side effect) [1] [4] Sudden breathlessness or pleuritic chest pain (which could indicate pulmonary embolism) Contact NHS 111 for urgent advice if you're unsure about the severity of your symptoms but are concerned
