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Aging 1 , 634650 (2021)

Induction of autoimmune disease by deletion of CTLA-4 in mice in adulthood

A spectrophotometer (Shimadzu UV-1700, Tokyo, Japan) was used to measure the optical density of the solution at 662 and 645 nm (for Ch a and b , respectively) and 470 nm (for TCAR)

In the acetylated form of the amino acid L-carnitine, carnitine is more readily absorbed and utilised by the body

This innate activation subsequently triggers adaptive immunity, with T and B lymphocytes serving as central mediators of intestinal inflammation in IBD (84) ( Figure 1 )

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