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As a result, these tumor cells become insensitive to KRAS inhibitors
443 These agents exert their anti-atherosclerotic effects through various mechanisms, including by improving blood lipid profiles, 444 preserving endothelial integrity and regulating endothelial function, 445 as well as modulating inflammatory processes
The no-DAC form (modified GRF 1-29) lacks that albumin anchor and acts for only minutes to a couple of hours
Translational success will depend on establishing standardized, benchmarked assays for ER and TrkB, supported by orthogonal phospho-proteomic verification to ensure inter-laboratory comparability
GIPR activation also influences lipid metabolism and adipose tissue function
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