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Most patients starting with normal b12 levels and no significant risk factors do not require supplementation

These therapeutic approaches aim to restore glutamatergic homeostasis and protect against excitotoxic neuronal cell death by selectively modulating iGluRs or glutamate levels

539 Results from several Phase III clinical trials (ORION-9/10/11, NCT03397121, NCT03399370, and NCT03400800) have shown that subcutaneous injections of inclisiran every 6 months considerably reduce LDL-C levels by 4852%, demonstrating sustained efficacy and good tolerability

So my response to that was just I was just crying all the time

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