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Although the degradation of PLGAs can be tuned from a few weeks to more than six months, exenatide PLGA microspheres fall short of a more desirable monthly administration, and the final product, Exenatide QW (Bydureon), was launched as a once-a-week product [96]

In that case, the patch could also be applied to the back, chest, or arms

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This is in contrast with the beneficial effects reported previously for the triagonist, in terms of reversion of adiposity excess and improved metabolic profile in diet-induced obese female mice 42 , suggesting that hyperandrogenism is bound to particular metabolic features that require specific multi-agonist treatments for maximum efficacy

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