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2011;105(9):13618 Goraya N, Simoni J, Jo C, Wesson DE

Similarly, the blood-CSF barrier is formed by the choroid plexus epithelium, controlling the exchange between the blood and the CSF, although allowing more molecules to cross compared to the BBB (Pardridge, 2011)

Therefore, cysteine may be a conditionally essential amino acid in individuals with SCD for the synthesis of GSH

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Another key factor is less intrinsic factor production