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While more research is needed in this area, a study looking at GLP1 receptor agonist use and opioid overdose risk in patients with type 2 diabetes and opioid use disorder (OUD) found that semaglutide was associated with reduced opioid overdose risk in patients with comorbid T2D and OUD

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Because of these potential risks, working closely with a healthcare provider is crucial to ensure the treatment is both safe and effective

doi: 10.1021/np1007262 256

Also, exenatide suppressed thrombus formation under flow conditions in ex vivo perfusion chambers using both human and mouse whole blood

Conclusion: Edoxaban was associated with a lower risk of both composite and ischemic outcomes in secondary stroke prevention