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Extended fasting beyond 16 hours should only be attempted under medical guidance, particularly if you have a history of disordered eating, diabetes, or cardiovascular concerns

Comparison Summary (2026 USA Data) Feature Intermittent Fasting Semaglutide (GLP-1) Typical Loss 25% body weight 1520% body weight Adherence Low (High dropout rate) High (85% maintain loss) Primary Benefit Autophagy & No Cost Appetite Control & Heart Health Difficulty High (Willpower required) LowModerate (Biological assist) 6

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Consider cutting back on caffeinated beverages while taking glutathione supplements