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Mullins RJ, Mustapic M, Chia CW, Carlson O, Gulyani S, Tran J, et al
Total clearance, CL = Hepatic clearance, CLH + Renal clearance, CLR + Intestinal clearance, CLI To model CL, we may apply dynamic modeling method such as physiologically based pharmacokinetic (PBPK) modelling
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After an online evaluation, patients can be prescribed compounded semaglutide, compounded tirzepatide, or compounded liraglutide depending on what a provider determines is appropriate
Tradjenta contains linagliptin, Januvia contains sitagliptin, and Nesina contains alogliptin, so they should not be substituted without clinician direction
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