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The clinical trials cited in the professional monographs for ALA and ALC were included in this review, with case reports, letters, and other reviews included only if the content contributed information unavailable in the cited clinical trials, such as additional adverse reactions

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GLP-1 receptor agonists have demonstrated measurable triglyceride-lowering effects in clinical trials, with reductions ranging from 15-30% depending on baseline lipid status and medication type

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264,265 Moreover, the extent of cardiac involvement is a major determinant of ATTR outcomes