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Extended use beyond 24 weeks has not been studied in the context of athletic performance

Consequently, various physiological stresses, which erythrocytes are exposed to (e.g., metabolic stress, temperature stress, mechanical stress, and deoxygenation), may affect their response to circulating CTS in blood by affecting RBC redox status

In another study examining patients with hypertension, renal medullary tissue oxygenation levels were significantly lower in a group of 20 African Americans compared with 29 Americans of European descent 30

Weeks 1 through 4: 1mg weekly

Dec 2015;67(12):1634-49

Manson, MD, DrPH, chief of the division of preventive medicine at Brigham and Womens Hospital and professor of Medicine at Harvard Medical School, tells SELF