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Other AEs reported with SGLT2i use include osmotic diuresis-related events and volume depletion-related hypotension, the latter of which tends to be more common in older adults, people with an eGFR of 3060 mL/min/1.73 m 2 , and in those taking loop diuretics [4]

It is indicated for patients with obesity (BMI 30 kg/m 2 ) or overweight (BMI 2729.9 kg/m 2 ) in the presence of at least one weight-related comorbidity [29, 30]

Diabetes Obes Metab 2017;19:1233-41.PubMed 59

Do not independently change a prescription dose because of nausea or other side effects

Understanding why these changes occur, what to expect, and when symptoms require medical attention helps patients manage treatment effectively whilst maintaining therapeutic benefits

Ultimately, the best way to avoid the itchy side effect depends on what's behind it