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These findings were supported by another large study that looked at the safety of semaglutide over a longer period of time (up to 2 years) and found no increased risk of cancer

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Practical tips to account for these fluctuations include: Weighing yourself at the same time each morning, after using the bathroom Tracking a weekly average rather than individual daily readings Noting lifestyle factors (stress, sleep quality, sodium intake, menstrual cycle stage) alongside weight data When to Speak to a GP About Unexpected Weight Changes Seek urgent care if sudden weight gain is accompanied by swelling, breathlessness, or chest pain