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A patellar tendon tear, also known as patellar tendon rupture, is when some or all of your patellar tendon tears apart

Scientific research Cagrilintide subject of active Novo Nordisk clinical program since 2018

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It acts primarily by upregulating collagen I, collagen III, and elastin synthesis in fibroblasts, and by modulating genes involved in antioxidant defense and matrix metalloproteinase balance

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Cartilage faces even greater obstacles given avascular nature (no blood vessels penetrating tissue), low cell density (chondrocytes sparse within extensive extracellular matrix), minimal metabolic activity (slow turnover and repair), and mechanical loading challenges (constant stress impeding healing)