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68 weeks both arms STEP 1 (NEJM 2021) vs STEP 2 (Lancet 2021)

After establishing an obesity model, mice were further divided into six groups: control group, liraglutide (LIRA) group, semaglutide (SEMA) group, high-fat diet (HFD) group, HFD + LIRA group, HFD + SEMA group, and subcutaneous injection for 4 weeks

They can help support hydration and prevent fatigue, especially if food intake is reduced.

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Kidney Function Tests: Including blood urea nitrogen (BUN) and creatinine tests to assess how well the kidneys are working, since kidney function can affect uric acid levels and vice versa