Myth #2: GLP-1 medication is a quick fix Its true that people who stop taking GLP-1 medications often regain some of the weight over the following months and years
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In diabetic patients with preserved EF, canagliflozin has proven to reduce the E/e ratio, a marker of diastolic dysfunction, after 3 months of treatment.40 In a small study including diabetic patients with established CV disease,41 empagliflozin led to reductions in the ventricular mass and significant improvements in diastolic function on tissue Doppler, also at 3 months
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Clinical studies demonstrate that semaglutide achieves glycemic control with HbA1c reductions of 1.5% to 1.8% at antidiabetic doses (Ozempic 0.5-1.0 mg, Rybelsus 7-14 mg) and produces weight loss ranging from 5-10% in type 2 diabetes and 12-15% with higher doses (Wegovy 2.4 mg) in patients with obesity
This small size belies its structural fragility