Liraglutide vs Semaglutide: How the Two GLP-1 Medications Compare Daily vs
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Some people may be prescribed 1.8 milligrams
The largest psychiatric safety meta-analysis to date found that GLP-1 medications were not associated with increased risk of serious psychiatric adverse events overall ( Pierret et al., JAMA Psychiatry, 2025 ), and a post-hoc analysis of the major semaglutide weight management trials found no differences in depression, suicidal ideation, or suicidal behavior compared to placebo ( Wadden et al., JAMA Internal Medicine, 2024 )
BMJ Case Rep 14(1):e235663