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Change in lipid profiles TC and LDL cholesterol concentrations in the CT group were significantly increased, while TC concentration in the LC group changed without any significant difference after short-term fasting as shown in Table 3

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Patients were considered persistent until evidence of discontinuation with no gaps between two consecutive prescriptions of more than 30 days for non-insulin agents and more than 3 months for insulin

Higher blood urea nitrogen is associated with increased risk of incident diabetes mellitus

This also drives further interest in using these medications outside of obesity and/or diabetes management with many already using them off-label for a wide variety of indications