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Persistent high levels, particularly without supplementation, may warrant further investigation to rule out medical conditions
For example, this study by Funk et al
Measuring diet success: why setting clear goals and tracking outcomes matter [A: 1:21:00, V: 1:33:51]
Common schedules include weekly injections for initial deficiency correction, then bi-weekly or monthly injections for maintenance, or as-needed for energy or performance boosts
Because it is largely free of those binding proteins, the analog stays active far longer than native IGF-1 a substantially extended half-life and more sustained systemic exposure