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2 Natural bioactive as multitarget therapeutics in metabolic and liver disorders Naturally occurring flavonoids help manage type 2 diabetes by modulating key glucose-metabolizing enzymes

La glioxalasa I cataliza la conversin de glutatin metilglioxal y glutatin reducido a SD-lactoil-glutatin

The compound moved through Phase I trials, which primarily assess safety in humans, and appeared to have a very favorable safety profile

& Pritzlaff, S

Their modes of operation frequently entail the regulation of cell signaling pathways that are vital for cellular function and survival

10.1016/j.clinph.2025.2110755 80 PedersenB