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Luteolin selectively inhibits the type of O-glycosylation (Mucin-type O -glycosylation) involved in the formation of amyloid- .[ref] Animal studies show luteolin inhibits neuroinflammation by controlling microglia activation.[ref] In a mouse study of Alzheimers, luteolin protects against amyloid memory dysfunction and also increases levels of endogenous antioxidants, including Mn-SOD, Cu/Zn-SOD, and glutathione

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Outcomes were not projected beyond a 1-year time horizon, and therefore cost and clinical outcomes were not discounted

2) Lip-1 reduces collagen deposition and pro-fibrotic factor expression in UUO mice and suppresses paracrine-driven fibroblast activation in human proximal tubular epithelial (HK-2) cells (116)