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De Lorgeril M, Salen P, Paillard F, Laporte F, Boucher F, de Leiris J (2002) Mediterranean diet and the French paradox: two distinct biogeographic concepts for one consolidated scientific theory on the role of nutrition in coronary heart disease

doi: 10.1016/j.ijbiomac.2020.03.009 69

By practicing intermittent fasting as part of a structured concussion therapy regimen, extended periods are created during which the body enters a metabolic state favorable to cellular repair

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Current animal model systems do not fully recapitulate the pathophysiological conditions in human IC/BPS, and targeting specific molecular pathway disruption in animal models might serve as a better option than existing models