The immune-mediated dysregulation of the MGB axis detailed in this review is observed not only in schizophrenia but also across various neurological disorders (241), including neurodevelopmental disorders (242), epilepsy (243), and depression (244), among others
GLP-1s reduce appetite
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We also used propensity score to match study groups on predefined characteristics, emulating participants randomizations using predefined stratifications criteria The study groups included: (1) GLP1-RA group: patients who initiated GLP1-RA, and (2) active comparator group, consisted of patients who initiated DPP4i, both initiated after meeting eGFR entry criteria
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Another, larger meta-analysis reported no reduction in HF hospitalizations but did observe improvements in tissue Doppler measurements and diastolic function, suggesting possible benefits in diastolic HF [33]