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Other studies have successfully used ethyl chloroacetoacetate as a starting material to produce ethyl (R)-4-chloro-3-hydroxybutyrate with high optical purity via asymmetric catalytic hydrogenation, which is then converted into L-carnitine

3-7 CVS consists of four phases, which are described below

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[DOI] [PubMed] [Google Scholar] 91.Cleven A.H., Al Sannaa G.A., Briaire-de Bruijn I., Ingram D.R., Van De Rijn M., Rubin B.P., De Vries M.W., Watson K.L., Torres K.E., Wang W.-L., et al

, 2019 , 123 (2), e263-e272

doi: 10.1016/j.jpsychores.2023.111230 248 GalleyJDNelsonMCYuZDowdSEWalterJKumarPSet al