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Surprisingly, mathematical modeling of these variations revealed that MAPK signaling negative feedback via IGF-1R reactivated MAPK signaling to mediate cancer cell drug resistance, highlighting the concomitant targeting of MEK and IGF-1R/MAPK signaling pathways as a potential therapeutic strategy in high-risk neuroblastoma
B., Lee, S
Estrogen isn't just about hot flashes and mood swings, it's a metabolic hormone
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38 GLP-1RAs increase microvascular blood flow in muscle tissue, enhance myocyte metabolism, inhibit muscle atrophy, and improve muscle mass and function
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