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Iranmanesh, A., Lizarralde, G

Treatment Goals in Diabetes Modern diabetes management focuses on: Achieving HbA1c targets Reducing body weight Preventing hypoglycemia Protecting the heart Preserving kidney function Improving quality of life Preventing long-term complications GLP-1 medications address many of these goals simultaneously

So when you see a patient, we want to do the lifestyle piece first, during, and after

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Given the increasing real-world use of combined therapy and the limited HF-specific evidence base, this review summarizes current data regarding the comparative and combined effects of GLP-1 receptor agonists and SGLT2 inhibitors in HF, with emphasis on efficacy, safety, mechanistic rationale, and evidence gaps