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This reaction requires the release of a methyl group from CH3-H4folate to H4folate, the two main circulating forms of folic acid (vitamin B9) in pigs (Natsuhori et al., 1996)
doi: 10.3390/ijms241512152 147 LiXMaoWChenJGodingCRCuiRXuZ-Xet al
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10.1038/nrdp.2016.12 62 YanH.XiaoF.ZouJ.QiuC.SunW.GuM.et al (2018)
Primary alkyl amines such as putrescine, spermidine, or the side chain of lysine are active second substrates (Schrode and Folk, 1978)
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