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Your Guide to Heavy Metal Detox Published: March 2022 Metals are all around us

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*SMD, standardized mean difference

A: 46 weeks refrigerated with BAC water

These DAMPs are recognized by PRRs in the skin (such as TLRs, NLRs), which trigger downstream signaling pathways like NF-B and MAPK pathways, and promote the production of inflammatory cytokines such as TNF-, IL-8, and IL-1 (63)