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More importantly, the downregulation of the EZH2 gene leads to a decrease in LAT1 ( SLC7A5 ) expression, and, in turn, the downregulation of LAT1 ( SLC7A5 ) or the depletion of essential amino acids can also induce a decrease in EZH2 expression (Dann et al., SLC7A5 ) indicates the potential of LAT1 ( SLC7A5 ) as a target for cancer therapy (Hafliger and Charles, In addition to regulating epigenetic methylase activity, metabolism also affects epigenetic enzymes involved in demethylation in cancer cells
One of the key functions of glutathione is its ability to neutralize free radicals, unstable molecules that can cause cellular damage and contribute to aging, chronic diseases, and various health conditions