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GSH and Aging GLUTATHIONE AND AGING--METABOLISM AND LIFE SPAN STUDIES 2014 Abstract Text: DESCRIPTION (Adapted from the Applicant's Abstract): Glutathione (GSH) is a major antioxidant present in high concentrations in nearly all living cells, with numerous critical functions in cellular homeostasis and defense

Conversely, p53-mutant MDA-MB231 breast tumor cells showed a high apoptosis rate exceeding 30%, along with a low percentage of cells undergoing senescence [94]

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Plasma levels decline with age from about 200 ng/mL at age 20 to roughly 80 ng/mL by age 60

Iron plays a central role in mitochondrial function and cellular energy production, particularly through its involvement in oxidative phosphorylation and the electron transport chain