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As GLP-1 therapy improves glucose control, this osmotic effect typically diminishes, potentially normalising previously excessive urination patterns

Several studies have demonstrated improvements in testosterone levels and certain semen parameters following treatment with GLP-1 receptor agonists. Reports involving liraglutide have shown improvements in sperm concentration, motility, morphology, and testosterone levels

Granhall C, Donsmark M, Blicher TM et al (2019) Safety and pharmacokinetics of single and multiple ascending doses of the novel oral human GLP-1 analogue, oral semaglutide, in healthy subjects and subjects with type 2 diabetes

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Effects of empagliflozin on markers of liver steatosis and fibrosis and their relationship to cardiorenal outcomes