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Jansson, L., Vrolix, K., Jahraus, A., Martin, K

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Notably, gene expression changes induced by heroin and cocaine in the VTA overlap significantly, indicating that different drugs regulate similar pathways through H3Q5dop in opposing directions 108

Excess fetal glucocorticoids can also interfere with normal brain growth and development at this time, with restraint stress to the dam during pregnancy leading to reduced levels of proteins such as growth-associated protein of 43 kDa (GAP-43) that are involved in synaptic pruning (Pfenninger et al., 1991