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Following near-total ablation of -cells in mice, -cells can transform into bihormonal (insulin + /glucagon + ) cells and subsequently into monohormonal insulin + cells (Thorel et al., 2010)

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2.3 Intracellular carnitine and derivatives The concentrations of carnitine, -butyrobetaine (BB), trimethyllysine (TML) and acetlycarnitine were determined in PBMC and erythrocyte lysate by tandem mass spectrometry according to Hirche et al