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However, once opened, consistent refrigeration is essential

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However, the half-life of natural GLP-1 in plasma is less than 2 min because it is rapidly enzymatically degraded by DPP-IV

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For the tirzepatide cohort, the maximum dose achieved varied, with one-quarter (25.9%) of the patients reaching the maximum dose of 15 mg and one-fifth of patients reaching maximum doses of 7.5 mg (19.6%), 10 mg (20.8%), and 12.5 mg (19.1%) each