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P., Tasker, J

Front Immunol (2020) 11:610363

Were talking about roughly 50% more weight loss with tirzepatide compared to semaglutide

Several medication classes may serve as alternatives when Ozempic side effects become problematic: SGLT2 inhibitors (like Jardiance, Farxiga, and Invokana) DPP-4 inhibitors Metformin Sulfonylureas Thiazolidinediones (TZDs) These medications work differently in the body and may cause fewer digestive side effects [17]

If cost is the actual driver, oral semaglutide is now a legitimate, FDA-approved answer rather than a compounded or device-manipulation workaround

Bhatt DL, Szarek M, Steg PG et al (2021) Sotagliflozin in patients with diabetes and recent worsening heart failure