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Recent studies of patients with sarcoidosis and SFN have shown that ARA 290 reduces neuropathic symptoms in conjunction with an increase of small nerve fibers as assessed by changes in the density of corneal nerve fibers (19)

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The human data are limited and largely open-label The most cited human evidence is the long-term follow-up work with the pineal extract epithalamin

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Results All of the injured rats that received BPC 157 exhibited consistent clinical improvement, increasingly better motor function of the tail, no autotomy, and resolved spasticity by day 15

Therapeutic modulation of these pathways, either via peptide analogs or receptor agonists, may offer targeted approaches to restore digestive function