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This phenomenon may help explain the obesity paradox, which suggests that, even though people who are obese are at greater risk of developing heart issues, once heart disease develops, individuals with higher BMIs appear to have a lower mortality risk than people with normal BMIs

Advanced glycation end products attenuate cellular insulin sensitivity by increasing the generation of intracellular reactive oxygen species in adipocytes

However, factors like stress, UV exposure, poor diet, and pollution can reduce your bodys natural levels

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Frequency: daily, every day of the cycle