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[24] Finally, a 2020 Cochrane systematic review found insufficient evidence to suggest that metformin monotherapy reduced all-cause mortality, serious adverse events, cardiovascular mortality, non-fatal myocardial infarction, non-fatal stroke, or end-stage renal disease when compared to DPP-4 inhibitors for the treatment of type 2 diabetes

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Arch Neurol, DOI: 10.1001/archneur.1992.00530350051019 Passeri, M., Cucinotta, D., Bonati, P

HGF promotes angiogenesis and neurogenesis, potentially improving nerve regeneration