Part 2 Insurance companies: Fixed margin Want costs to rise predictably and steadily, not by surprise In support of GLP1s over time, not immediately, so they can be priced in PBMs: Benefit from higher priced drugs with rebates Pharmacies: Benefit from volume of prescriptions Benefit from foot traffic from prescriptions Pharma: Benefit from blockbuster drugs Summary of existing players: four key stakeholders benefit from higher priced blockbusters drugs over a long-term time horizon under most circumstances
The working theory is that GLP-1s protect the heart through a combination of better metabolic control, lower inflammation, and direct vascular and cardiac benefits
The subcutaneous injection can be administered at any time of day, with or without food, providing additional flexibility
Some common side effects include nausea, vomiting, diarrhea, and constipation, especially when starting or increasing the dose
Research realistic costs and affordable options for legitimate treatments
How does tirzepatide compare to semaglutide and retatrutide