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doi: 10.1083/jcb.105.2.1023 87

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This leads to megaloblastic anemia, which is characterized by large, immature red blood cells

F36 and F135 in TM1 and TM4 respectively are on 4.4 distance effectively closing the entry from the lipid bilayer

After 8 weeks of treatment, the positive effects were more pronounced for all the clinical skin parameters quantified, and the fibroblasts experiment confirmed the stimulatory impact on dermal health parameters