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Ethics declarations Ethical approval for the research project protocol was obtained from the Research Ethics Committee at Damietta University (Subcommittee for the Basic Sciences Sector, Faculties of Science and Agriculture) under reference number DuRec No

S.KhirasariaR

The authors reported statistically significant mean reductions in body weight from baseline across the retatrutide dose groups relative to placebo, with gastrointestinal adverse events the most frequently reported findings, consistent with the incretin-agonist class

The phenomenon of clasmatodendrosis

Authors' contributions LH performed the histological examination of the kidney and YS performed the molecular biology experiments

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