Anti-obese property of fucoxanthin is partly mediated by altering lipid-regulating enzymes and uncoupling proteins of visceral adipose tissue in mice
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For instance, galangin downregulated TRPV1, CGRP, and substance Pkey nociceptive markers involved in visceral hypersensitivity and gastric pain in models of ethanol-induced mucosal injury
Transcription factor NFR-2 is negatively regulated, principally by KEAP1, via the polyubiquitin pathway by proteasomal degradation