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In 2024, Able and colleagues published a study in the International Journal of Impotence Research using the TriNetX database [1]

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Estradiol increases the sensitivity of ventral tegmental area dopamine neurons to dopamine and ethanol

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Moreover, it was observed that the persistence of the virus in infected cells involves mitochondrial ROS production modulated by viral protein p13 [18]

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Ultimately, this information can be used prospectively for patient selection in clinical trials, screening individuals for these safety biomarkers to identify and exclude those with high risk of adverse events

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