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Disulfide bond scrambling While tirzepatide does not contain traditional disulfide bonds, it does contain a C20 fatty diacid chain attached via a linker to a lysine residue

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Important safety considerations during the initial treatment period include: Monitoring for severe gastrointestinal symptoms: Persistent vomiting, severe abdominal pain, or signs of pancreatitis (severe upper abdominal pain radiating to the back) require immediate medical evaluation

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doi: 10.1016/J.MOLMET.2019.09.010 [DOI] [PMC free article] [PubMed] [Google Scholar] 70.Kjems LL, Holst JJ, Vlund A, Madsbad S