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Importantly, the combination of anti-PD-1 therapy with MEK1/2 inhibitors significantly enhanced cytotoxicity, suggesting that PD-1/PD-L1 expression may serve as a predictive biomarker to guide combination immunotherapy in PDAC

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SIRT2 inhibition results in meiotic arrest, mitochondrial dysfunction, and disturbance of redox homeostasis during bovine oocyte maturation

A., Brandt, J

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