A single overnight exposure at 15C can reduce bioavailability by 1520%, while exposure above 30C for even two hours can denature the peptide structure entirely, rendering it biologically inactive regardless of subsequent refrigeration
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Thats important because it expands the number of people who could benefit from the drug, says Tiffany Powell-Wiley, a cardiologist and epidemiologist at the National Heart, Lung and Blood Institute in Bethesda, Md
MonaghanG.RyanM.SeddonR.HumeR.BurchellB.1996Genetic variation in bilirubin UPD-glucuronosyltransferase gene promoter and Gilberts syndrome.3479001(March 1996),578581,0140-6736 82
